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SKU
RXSOL-60-6604-569

Title
ETHYL TRI FLUORO ACETATE

Ethyl trifluoroacetate is used as an intermediate in organic synthesis to prepare organic fluorine compounds like 3-ethyl-1-methylimidazolium trifluoroacetate (EMITA). It is involved in the syntheses of various pharmaceutically active molecules and agricultural products.

Field Note

Note
  1. Moisture Sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and strong acids.
Application
  1. Ethyl trifluoroacetate can be used:
    • To synthesize cyclopentenones or furans containing trifluoromethyl group from aromatic ynones.
    • In the selective trifluoroacetylation of anilines catalyzed by 4-dimethylaminopyridine.
    • As a starting material in the two-step electrosynthesis of trifluoroacetyltrimethylsilane (CF3COSiMe3).
    • In the preparation of trifluoromethyl ketones via trifluoroacetic ester/ketone metathesis with alkyl aryl ketones.
    • To synthesize o-fluorinated trifluoro acetophenones from substituted fluorobenzene.

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